Electrophysiology of Cardiac muscles and Antiarrhythmic agents
نویسندگان
چکیده
منابع مشابه
Effectiveness of Antiarrhythmic Agents
Hughes S: Effect of prazosin vs placebo on chronic left ventricular heart failure. Circulation 59: 344, 1979 12. Curtiss C, Cohn JN, Vrobel T, Franciosa JA: The role of the renin-angiotension system in the systemic vasoconstriction of chronic heart failure. Circulation 58: 763, 1978 13. Packer M, Meller J, Gorlin R, Herman MW: Hemodynamic and clinical tachyphylaxis to prazosin-mediated afterloa...
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Background. A main side effect of antiarrhythmic drug therapy is the tendency of these drugs to promote arrhythmia within the therapeutic concentration range, i.e., the proarrhythmic activity of these drugs. However, a model for in vitro assessment, quantification, and comparison of proarrhythmic drug activities was still lacking, and only sparse data were available. Methods and Results. To ana...
متن کاملCardiac Electrophysiology
Recently, significant achievements have beenmade in cardiac electrophysiology research, including Ca regulatory pathways, membrane ion channel-related intracellular signaling, and electrical remodeling in cardiomyopathies. The rapid progress in the basic research has led to applications of numerous new methods and strategies to clinical diagnoses and treatments. The efficacy of antiarrhythmic p...
متن کاملElectrophysiology of acanthocephalan body wall muscles.
Body wall muscles of an acanthocephalan Macracanthorhynchus hirudinaceus were studied by means of scanning and light microscopy and intracellular recording of potentials. Three types of spontaneous potential changes were found: larger (L) potentials which usually exhibited overshoot and were as large as 65 mV; smaller symmetric (A) potentials approximately 15 mV in amplitude; and even smaller a...
متن کاملAntiarrhythmic agents: modulated receptor applications.
IT IS NOW well established that block of transmem-brane ionic channels is frequently time and voltage dependent.' 2 Although the modulated receptor theory has been most extensively studied for sodium and calcium channels in cardiac tissue,3 it may apply to other membrane receptors as well. The present essay is limited to discussion of sodium-channel blockers and how their time-and voltage-depen...
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ژورنال
عنوان ژورنال: Japanese Journal of Electrocardiology
سال: 1983
ISSN: 1884-2437,0285-1660
DOI: 10.5105/jse.3.3